Is Psoriasis a Serious Health Condition? How to Get Rid of Psoriasis Fast?

Patients receiving treatments for severe psoriasis have a 41% increased risk of dying from malignancy than patients without psoriasis. Risk of malignancy attributable to psoriasis itself remains uncertain. A meta-analysis of 11 observational studies evaluating the risk of malignancy among patients with psoriasis suggested that overall risk of cancer, excluding nonmelanoma skin cancers (NMSCs), is increased (standardized incidence ratio, 1.16 [95% CI, 1.07–1.25]).Greater risks of upper aerodiges- tive tract, respiratory tract, liver, pancreas, urinary tract cancers and lymphoma were also suggested. The level of heterogeneity among the included studies was high, making interpretation challenging. In addition, many studies did not account for important confounding factors, such as smoking and drinking, or assess psoriasis treatment effects on the risk of subsequent malignancy, calling into question the validity of attributing the increased risk of cancer to psoriasis alone. A subsequent cohort study of cancer risk among patients with psoriasis in the United Kingdom that included information on BMI, smoking, and drinking also found increased risks of lung cancer, NMSC, and lymphoma, supporting some of Pouplard et al’s findings.

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